The term atypical fibroxanthoma (AFX) was used in 1961 by Helwig for indicate a typically nodular ulcerative lesion arising from the sun-exposed skin of the head and neck. Rarely AFX has been described in young and in areas without evidence of actinic damage.

Atypical fibroxanthoma (AFX) is a tumor that occurs primarily in older individuals after the skin of the head and neck has been damaged significantly by sun exposure and/or therapeutic radiation. Clinically, lesions usually are suggestive of malignancy because they arise rapidly (over just a few weeks or months) in skin in which other skin ca

Recurrence rates of 5% to 10% following wide excision have been reported [13-15]. Nov 16, 2015 Atypical fibroxanthoma (AFX) is a rare, low-grade malignant Complete excision with safety margins is recommended as a treatment strategy. An Atypical Fibroxanthoma (AFX) is an uncommon type of skin cancer, accounting for less than 0.2 % of all skin cancers. It occurs mainly on the head or neck of Atypical fibroxanthoma (AFX) is an undifferentiated pleomorphic sarcoma that simply represent residual disease related to inadequate surgical margins [10]. Nine cases of an unusual presentation of atypical fibroxanthoma that we In case 3, surgical margins were inadequate; the tumor recurred 8 months after first Surgical excision with clear margins. Epidemiology[edit].

Atypical fibroxanthoma margins

However, AFX may occur on the trunk, extremities and in sun-protected areas of the body. It may also occur on skin where other Atypical fibroxanthoma (AFX) is a dermal mesenchymal neoplasm arising in sun-damaged skin, primarily of the head and neck region of older men. Conservative excision cures most. However, varying degrees of subcutaneous involvement can lead to a more aggressive course and rare metastases.

The elevated, ulcerated, and nodular characteristics are apparent. (WU neg.

Atypical fibroxanthoma (AFX) is an uncommon, pleomorphic, spindle cell cutaneous malignancy that most commonly presents as a solitary red or pink papule or nodule on the head or neck (picture 1A) [ 1 ]. Exposure to ultraviolet light most likely contributes to the development of AFX.

Abstract. Atypical fibroxanthoma (AFX) is a rare skin neoplasm of low-grade malignancy and fibroblastic origin. AFX is a curable cutaneous disease and the diagnosis depends on knowledge of its clinical and histological features and combined immunohistochemistry markers.

margins on recent excision; or; Rapidly growing lesions in any anatomic area; or Apocrine/eccrine carcinoma; Atypical fibroxanthoma; Bowenoid papulosis

The patient did well until January, 1976, when he first noted'a nodule at the previously involved site.

The majority of cases were found in the Dresden region. CONCLUSION: Atypical fibroxanthoma demonstrates an uneven geographic distribution in southeast Germany that demands further investigations.
Hemnet halland

AFX was first reported by Helwig in the early 1960s and is characterized as a neoplasm of low-grade malignancy of fibroblastic origin. AFX generally occurs on the actinic-damaged skin of the elderly, especially on the face and scalp.

A Atypical fibroxanthoma rarely recurs after complete excision with clear margins. Recurrence and metastasis are more likely in people that are immunosuppressed.
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Narrow or inadequate margins have been cited as a potential cause of recurrence in several series [5]. However, there have been no clear guidelines References quantifying this. Atypical fibroxanthoma is described as having a benign 1. Helwig EB (1963) Atypical fibroxanthoma.

In the case of AF patients had a facial tumor with no metastases and that probably it was a local recurrence of Recurrence of atypical fibroxanthoma. Diagnosis and treatment. Mattiola et al. Atypical fibroxanthoma (AFX), is a rare type of skin cancer affecting older individuals with sun damaged skin.